Alglucosidase Alfa

Alglucosidase Alfa treats Pompe disease. Ask your doctor about the Pompe Registry.

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Uses of Alglucosidase Alfa

Alglucosidase alfa is a prescription medication used to treat patients with Pompe disease.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Alglucosidase Alfa Brand Names

Alglucosidase Alfa may be found in some form under the following brand names:

  • Lumizyme

  • Myozyme

Alglucosidase Alfa Drug Class

Alglucosidase Alfa is part of the drug class:

  • Enzymes

Side Effects of Alglucosidase Alfa

Serious side effects have been reported with alglucosidase alfa. See the “Alglucosidase Alfa Precautions” section.

Common side effects of alglucosidase alfa include the following:

  • infusion-related reactions
  • severe allergic reactions
  • hives
  • diarrhea
  • vomiting
  • shortness of breath
  • itchy skin
  • skin rash
  • redness of skin
  • neck pain
  • partial hearing loss
  • flushing/feeling hot
  • pain in extremities
  • chest discomfort
  • pneumonia
  • respiratory failure
  • respiratory distress
  • respiratory syncytial virus infection
  • gastroenteritis
  • fever
  • sore throat

This is not a complete list of alglucosidase alfa side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Alglucosidase Alfa FDA Warning


Life-threatening anaphylactic reactions, severe allergic reactions and immune mediated reactions have been observed in some patients during alglucosidase alfa infusions. Therefore, appropriate medical support should be readily available when alglucosidase alfa is administered.

Warning: CARDIORESPIRATORY FAILURE for Myozyme (alglucosidase alfa):

Risk of Cardiorespiratory Failure patients with compromised cardiac or respiratory function may be at risk of serious acute exacerbation of their cardiac or respiratory compromise due to infusion reactions, and require additional monitoring.


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